| Date | Location | Result | |
| 3/21/10 | Cincinnati, OH (Cintas Center) | Xavier 94, East Tennessee State 82 | |
| 3/6/10 | Macon, Ga. | ETSU 63, North Florida 62 | |
| 3/5/10 | Macon, Ga. | ETSU 77, Belmont 63 | |
| 3/3/10 | Macon, Ga. | ETSU 84, Stetson 49 | |
| 2/27/10 | Veterans Memorial Arena | ETSU 79, Jacksonville 70 | |
| 02/25/10 | Jacksonville, Fla. (UNF Arena) | ETSU 68, North Florida 58 | |
| 2/22/10 | MSHA Athletic Center (Johnson City, TN) | ETSU 88, USC Upstate 67 | |
| 02/18/10 | Buies Creek, N.C. (Gore Arena/Pope Ctr) | ETSU 77, Campbell 67 | |
| 2/13/10 | MSHA Athletic Center (Johnson City, TN) | ETSU 81, Kennesaw State 63 | |
| 2/11/10 | MSHA Athletic Center (Johnson City, TN) | ETSU 83, Mercer 71 | |
| 02/06/10 | DeLand, Fla. (Edmunds Center) | ETSU 57, Stetson 55 | |
| 2/4/10 | Fort Myers, Fla. (Alico Arena) | Florida Gulf Coast 92, ETSU 55 | |
| 2/01/10 | MSHA Athletic Center (Johnson City, TN) | ETSU 87, Belmont 65 | |
| 1/30/10 | MSHA Athletic Center (Johnson City, TN) | ETSU 82, Lipscomb 59 | |
| 1/27/10 | MSHA Athletic Center (Johnson City, TN) | ETSU 88, Campbell 65 | |
| 01/23/10 | Nashville, Tenn. (Curb Event Center) | ETSU 81, Belmont 67 | |
| 01/21/10 | Nashville, Tenn. (Allen Arena) | East Tennessee State 76, Lipscomb 65 | |
| 1/16/10 | MSHA Athletic Center (Johnson City, TN) | ETSU 88, FGCU 83 | |
| 1/14/10 | MSHA Athletic Center (Johnson City, TN) | ETSU 78, STET 59 | |
| 1/9/10 | University Center | ETSU 81, Mercer 60 | |
| 01/07/10 | Kennesaw, Ga. (KSU Convocation Center) | East Tennessee State 90, Kennesaw State 59 | |
| 01/04/10 | Spartanburg, S.C. (Hodge Center) | USC Upstate 85, ETSU 78 | |
| 12/31/09 | Carmichael Arena, Chapel Hill | North Carolina 104, East Tennessee State 65 | |
| 12/28/09 | Memorial Gymnasium, Nashville, Tenn. | Vanderbilt 96, ETSU 83 | |
| 12/21/09 | MSHA Athletic Center (Johnson City, TN) | ETSU 77, JU 72 | |
| 12/17/09 | Boone, N.C. (Holmes Center) | Appalachian State 92, ETSU 87 | |
| 12/5/09 | Memorial Center (Johnson City, Tenn.) | ETSU 82, UNF 54 | |
| 11/29/09 | Honolulu, HI (Stan Sheriff Center) | East Tennessee State 94, Hawai'i 83 | |
| 11/28/09 | Honolulu, HI (Stan Sheriff Center) | Arizona State 80, East Tennessee State 67 | |
| 11-22-09 | Fayetteville, Ark. (Bud Walton Arena) | Arkansas 95, ETSU 78 | |
| 11/15/09 | Starkville, Miss. (Humphrey Coliseum) | Mississippi State 80, East Tennessee State 50 | |
| 11/13/09 | Memorial Center (Johnson City, Tenn.) | ETSU 85, UTC 61 |